プラズマの抗酸化物質濃度と血圧に対する果物と野菜の摂取の影響:ランダム化制御試験
J H John1, S Ziebland, P Yudkin
1Division of Public Health and Primary Health Care, Department of Primary Health Care, University of Oxford, Oxford, UK
Lancet (London, England)
|June 22, 2002
まとめ
食事療法による果物や野菜の摂取量の増加は,抗酸化物質のレベルを大幅に高め,成人では血圧を下げる. この研究では,一般の人々の心血管健康に対する長期的な利点が示されています.
科学分野:
- 栄養科学とは,栄養科学である.
- 予防的な心臓病学
- 公共衛生の介入 公共衛生の介入
背景:
- 高量の果物や野菜の摂取は,がんや心血管疾患 (CVD) のリスクの低下と関連しています.
- 短期的なダイエット介入は有望だが,一般人における長期的な効果は不明である.
- 果物と野菜の消費量の増加が重要な健康指標に与える影響を評価することは極めて重要です.
研究 の 目的:
- 果物と野菜の消費を増やすことを目的とした食事介入の長期的な効果を評価する.
- 血の抗酸化物質濃度,果物と野菜の毎日の摂取量,血圧の変化を測定する.
- 簡潔な交渉法が,プライマリケア環境における食事の変化を促進する際の有効性を判断する.
主な方法:
- 6ヶ月のランダム化対照試験は,健康な成人690人 (25~64歳) を対象に実施されました.
- 参加者は,初等医療保健センターから募集されました.
- 簡潔な交渉法を使用して,少なくとも5分の1の果物と野菜を毎日摂取することを奨励しました.
主要な成果:
- アルファカロテン,ベータカロテン,ルテイン,ベータクリプトキサンチン,アスコルビック酸の血濃度の大幅な増加が介入グループで観察されました.
- 自己報告した果物と野菜の摂取量は,介入グループで1日平均1.4食分増加した (p<0.0001).
- シストリック血圧は,対照群と比較して,介入群で4.0mmHg (p<0.0001) 減少し,ダイアストリック血圧は1.5mmHg (p=0.02) 減少した.
結論:
- この介入により,果物と野菜の摂取量と血の抗酸化物質濃度が効果的に増加しました.
- 血圧の減少は,一般人における心血管疾患リスクの低下の可能性を示唆しています.
- 簡潔な交渉方法は,健康的な食習慣を促進し,健康に重大な利益をもたらすための成功した戦略である可能性があります.
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