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Updated: Jul 6, 2026

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
08:46

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms

Published on: December 9, 2015

人間の遺伝子におけるエクソニック・スプライシング・エンハンスターの予測的識別

William G Fairbrother1, Ru-Fang Yeh, Phillip A Sharp

  • 1Department of Biology, Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|July 13, 2002
PubMed
まとめ

研究者らは,遺伝子のスプライシングに不可欠なエクソニック・スプライシング・エンハンスター (ESE) を特定した. 新しい計算ツールであるRESCUE-ESEは,ESEの活動と,遺伝子スプライシングに対する突然変異の影響を正確に予測します.

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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

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