静脈早発刺激の結合間隔が血圧と心拍の渦巻に及ぼす影響
Mari A Watanabe1, Joseph E Marine, Robert Sheldon
1Harvard-Thorndike Institute of Electrophysiology, Beth Israel Deaconess Medical Center, Boston, Mass, USA. mwata001@udcf.gla.ac.uk
Circulation
|July 18, 2002
まとめ
心拍の乱れ (HRT) は,プログラムされた電気刺激によって誘発される可能性があります. この設定では,心拍数がHRTに影響し,心室早産複合性早産ではなく,HRTを測定するための有効な方法を示唆します.
科学分野:
- 心臓病学 心臓病学
- 電気生理学 電気生理学
- 自律神経系の機能 自律神経系の機能
背景:
- 心拍の乱れ (HRT) は,心筋梗塞後の死亡率の非侵襲的なリスク分層化ツールです.
- 以前の研究では,心房早発症複合結合間隔と交感活動がHRTと関連していた.
- この研究では,プログラムされた刺激誘発型HRTと電気生理学的パラメータの関係を調べました.
研究 の 目的:
- プログラムされた電気刺激がHRTを確実に誘発できるかどうかを判断する.
- 室腔早産複合体の早産とカップリング間隔がHRTパラメータに与える影響を評価する.
- コントロールされた環境で心拍数とHRTの測定値の関係を探求する.
主な方法:
- 28人の患者は,右心室頂部からの外刺激でプログラムされた電気刺激を受けた.
- 静脈早発複合結合の間隔は,屈折性になるまで徐々に短縮された.
- 渦巻の傾き (TS),渦巻のタイミング (TT),および渦巻の発生が計算され,カップリング間隔と補償的な一時停止と相関しました.
- 動脈血圧を継続的にモニターした.
主要な成果:
- HRTは,プログラムされた刺激によって誘発される可能性があります.
- 異常なTSと乱流の発症は,それぞれ4人と13人の患者で観察されました.
- HRTのパラメータは,カップリングインターバルまたは補償休止と限られた相関を示しました.
- 心拍数とTS/TTとの間に有意な相関が認められ,高い心拍数が低いTSと遅いTTに関連していた.
結論:
- プログラムされた電気刺激は,HRTのパラメータを誘発および測定するための有効な方法であり,特に,まれな心室早産複合体の患者では特に有効です.
- 心拍数は,心室早産複合早産ではなく,誘発されたHRTに大きな影響を与える.
- 発見は,この文脈でのHRT測定は,心拍数に関連する自律的調節によって影響されることを示唆しています.
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