関連する実験動画

Updated: May 3, 2026

A Semi-Quantitative Drug Affinity Responsive Target Stability DARTS assay for studying Rapamycin/mTOR interaction
05:28

A Semi-Quantitative Drug Affinity Responsive Target Stability DARTS assay for studying Rapamycin/mTOR interaction

Published on: August 27, 2019

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ラパミシン (TOR) の標的の結合パートナーであるラプターは,TORの作用を媒介する

Kenta Hara1, Yoshiko Maruki, Xiaomeng Long

  • 1Biosignal Research Center, Kobe University, 657-8501, Kobe, Japan. harak@kobe-u.ac.jp

Cell
|August 2, 2002
PubMed
まとめ

ラプターはmTORと結合し,4EBP1.1のような重要な標的をリン酸化できるようにする重要なタンパク質の支架です. この相互作用は,細胞の成長を調節し,TORシグナリングを vivo で媒介するために不可欠です.

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