Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Adhesion01:14

Adhesion

44.5K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
44.5K
Frequency-dependent Selection01:21

Frequency-dependent Selection

24.2K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
24.2K
Drug Dependence01:17

Drug Dependence

1.7K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.7K
Contact-dependent Signaling01:19

Contact-dependent Signaling

47.6K
Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
47.6K
Cell Adhesion in Plants01:14

Cell Adhesion in Plants

3.4K
Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
3.4K
Bacterial Transformation01:33

Bacterial Transformation

60.1K
In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
60.1K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Loss of essential outer membrane functions causes drug hypersensitization in <i>Acinetobacter baumannii</i> overexpressing multidrug efflux pumps.

mBio·2026
Same author

Pathological assessment of tumour beds in breast excisions post-neoadjuvant therapy: a retrospective cohort study.

Histopathology·2026
Same author

The transcriptional response of <i>Yersinia pseudotuberculosis</i> to macrophage-released chemicals during growth within synthetic microcolonies.

bioRxiv : the preprint server for biology·2026
Same author

RNA Quality Control Enables Antibiotic Tolerance.

bioRxiv : the preprint server for biology·2026
Same author

Host CD59 Potentiates the Type III Secretion System in <i>Yersinia pseudotuberculosis</i>.

bioRxiv : the preprint server for biology·2026
Same author

Resistance, heteroresistance, and fitness costs drive colistin treatment failure during <i>Acinetobacter baumannii</i> pneumonia.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
関連記事をすべて見る

関連する実験動画

Updated: Feb 10, 2026

In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions
10:24

In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions

Published on: June 11, 2015

11.3K

宿主との踊り; 流れに依存する細菌の粘着.

Ralph R Isberg1, Penelope Barnes

  • 1Howard Hughes Medical Institute, Boston, MA 02111, USA. ralph.isberg@tufts.edu

Cell
|August 2, 2002
PubMed
まとめ
この要約は機械生成です。

宿主細胞へのバクテリアの粘着は,コロニー化にとって極めて重要です. 剪定ストレスによって強化された特定のピリは,上皮質のような宿主表面への細菌の結合を改善します.

さらに関連する動画

Introducing Shear Stress in the Study of Bacterial Adhesion
13:28

Introducing Shear Stress in the Study of Bacterial Adhesion

Published on: September 2, 2011

16.3K
Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
10:10

Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells

Published on: October 26, 2009

18.7K

関連する実験動画

Last Updated: Feb 10, 2026

In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions
10:24

In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions

Published on: June 11, 2015

11.3K
Introducing Shear Stress in the Study of Bacterial Adhesion
13:28

Introducing Shear Stress in the Study of Bacterial Adhesion

Published on: September 2, 2011

16.3K
Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
10:10

Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells

Published on: October 26, 2009

18.7K

科学分野:

  • 微生物学 微生物学とは
  • 細胞生物学 細胞生物学
  • バイオフィジックス 生物物理学

背景:

  • ユカリオット宿主に対する細菌の植民には,宿主細胞に直接結合することが必要である.
  • 粘着はしばしば腸内細菌のピリ上にあるレクチンによって媒介される.
  • Pili媒介による粘着は,シアストレスのような機械的な力によって影響を受けることがあります.

研究 の 目的:

  • バクテリアの粘着におけるシアストレスの役割を調査する.
  • レクチン媒介の皮粘着のメカニズムを理解するために.

主な方法:

  • バイオ物理学的技術を用いて,ピリ-宿主細胞の相互作用を研究する.
  • 体外での生理学的切断ストレス条件をシミュレートする.

主要な成果:

  • 特定のピリが剪定ストレス下での付着力が強化されていることが実証されました.
  • 剪定依存的結合において重要なレクチン機能を特定した.
  • バクテリアの植民地化における機械力の重要性を示した.

結論:

  • 切断ストレスは,特定の piliによって媒介された細菌の粘着を大幅に強化します.
  • レクチン媒介のピリは,腸内細菌がフロー条件下で宿主表面にニッチを確立するための鍵です.