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関連する概念動画

Receptor-mediated Endocytosis01:38

Receptor-mediated Endocytosis

Overview
Receptor-mediated Endocytosis01:20

Receptor-mediated Endocytosis

Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
Clathrin-Mediated Endocytosis of LDL
One well-characterized example of receptor-mediated endocytosis is the...
Immunogold Electron Microscopy01:20

Immunogold Electron Microscopy

Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.
Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...
Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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関連する実験動画

Updated: Jul 16, 2026

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications
14:43

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

Published on: September 23, 2013

感受性半導体インターフェイスでリガンド局所化された電子トラップ.

Paul G Hoertz1, David W Thompson, Lee A Friedman

  • 1Department of Chemistry, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.

Journal of the American Chemical Society
|August 15, 2002
PubMed
まとめ

メソポラスTiO2膜に誘導されたルテニウムとオスミウム複合体は,超高速の電子注入と長寿命の電荷分離状態を示します. 太陽エネルギー変換に不可欠なこれらの中間物質は,観測可能であり,その動態が特徴付けられています.

科学分野:

  • マテリアルサイエンス 材料科学
  • フォトケミストリー フォトケミストリー
  • 電気化学 電気化学について

背景:

  • ナノ結晶型,メソポラス型二酸化チタン (TiO2) 薄膜は,先進的な材料の応用における重要な構成要素です.
  • ルテニウム (Ru) とオスミウム (Os) のポリピリジル複合体は,その光物理学的性質のために広範に研究されています.

研究 の 目的:

  • TiO2フィルムに誘導されたRuとOs複合体のインターフェイス電子伝送ダイナミクスを調査する.
  • 興奮状態と電荷分離中間物質の形成,寿命,および性質を特徴づける.

主な方法:

  • 特定のRuおよびOs複合体を持つTiO2膜の表面派生.
  • 還元ポテンシャルを決定するための電気化学測定.
  • ナノ秒パルスレーザー刺激による一時的吸収スペクトロスコーピーは,興奮状態と中間物質を検出します.
  • 量子力学では,様々な刺激波長での測定結果が得られます.

主要な成果:

  • 複合体 [Ru(bpy) 2 ((deebq) ] ((PF6) 2) と [Os ((bpy) 2 ((deebq) ] ((PF6) 2) は,定義された表面覆いを持つTiO2に結合する.
  • TiO2への超高速電子注入が観察され,その後にリガンド局所化されたトラッピングが観察されます.

さらに関連する動画

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
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Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

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Detection of Ligand-activated G Protein-coupled Receptor Internalization by Confocal Microscopy
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Detection of Ligand-activated G Protein-coupled Receptor Internalization by Confocal Microscopy

Published on: April 9, 2017

関連する実験動画

Last Updated: Jul 16, 2026

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications
14:43

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

Published on: September 23, 2013

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
11:17

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

Detection of Ligand-activated G Protein-coupled Receptor Internalization by Confocal Microscopy
10:24

Detection of Ligand-activated G Protein-coupled Receptor Internalization by Confocal Microscopy

Published on: April 9, 2017

  • 長寿命の電荷分離型中間物質 (MII ((deebq-) ((bpy) 2+/TiO2およびMIII ((deebq) ((bpy) 23+/TiO2) が形成され,その濃度は肉眼で観察できる.
  • 電荷分離状態形成の量子収量は,刺激波長に依存しています.
  • 結論:

    • この研究は,超高速の電子注入と,その後のトラッピングを含むメカニズムを明らかにし,長寿命の電荷分離状態につながる.
    • 観測された中間物質とそのミリ秒スケールの衰退運動は,これらのシステムにおけるエネルギー変換プロセスを理解するために重要である.
    • 発見は,太陽電池などのアプリケーションのための効率的な光活性材料の設計に関する洞察を提供します.