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Updated: Jul 24, 2026

An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions
08:40

An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions

Published on: March 14, 2016

糖タンパク質イバルファとその複合体とフォン・ウィレブランド因子A1ドメインの構造

Eric G Huizinga1, Shizuko Tsuji, Roland A P Romijn

  • 1Department of Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands. e.g.huizinga@chem.uu.nl

Science (New York, N.Y.)
|August 17, 2002
PubMed
まとめ

血小板グリコタンパク質イバルファ (GpIbalpha) とフォン・ウィレブランド因子 (VWF) の相互作用は,血液の凝固の鍵です. 私たちは,それらの複雑な構造を提示し,出血障害と抗血栓性薬の開発に関する洞察を明らかにします.

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Protein Organization01:13

Protein Organization

Overview
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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Protein and Protein Structure

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Globular and Fibrous Proteins

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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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Type IV Collagen of Basal Lamina

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