関連する実験動画

Updated: Jul 19, 2026

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
08:47

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation

Published on: March 5, 2018

ミトコンドリアの浸透性より前のストレス誘発性アポトーシスにおけるカスパゼ-2の必要性

Patrice Lassus1, Ximena Opitz-Araya, Yuri Lazebnik

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Science (New York, N.Y.)
|August 24, 2002
PubMed
まとめ

細胞毒性ストレスとサイトカインシグナル伝達の両方がアポトーシスを引き起こす. この研究は,ストレスによるカスパース-2の活性化がミトコンドリアの浸透性にとって極めて重要であり,細胞死経路を増幅することを明らかにしています.

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