関連する実験動画

Updated: May 10, 2026

One-channel Cell-attached Patch-clamp Recording
13:07

One-channel Cell-attached Patch-clamp Recording

Published on: June 9, 2014

MscLのオープンチャネル構造と機械敏感チャネルのゲートメカニズム

Eduardo Perozo1, D Marien Cortes, Pornthep Sompornpisut

  • 1Department of Molecular Physiology and Biological Physics, and Center for Structural Biology, University of Virginia, Charlottesville, Virginia 22906, USA. eperozo@virginia.edu

Nature
|August 29, 2002
PubMed
まとめ

メカノセンシティブチャネル (MSC) は,物理的な力を感知する上で極めて重要です. この研究は,機械感受性チャンネルである MscL の構造的変化を閉じた状態から開いた状態へと明らかにし,ゲーティングメカニズムを明らかにします.

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