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Updated: Jul 7, 2026

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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転写活性化の構造的基礎:CAP-α CTD-DNA複合体

Brian Benoff1, Huanwang Yang, Catherine L Lawson

  • 1Waksman Institute and Department of Chemistry, Howard Hughes Medical Institute, Rutgers University, Piscataway, NJ 08854, USA.

Science (New York, N.Y.)
|August 31, 2002
PubMed
まとめ

結晶構造は,Escherichia coliのカタボライト活性化タンパク質 (CAP) が,RNAポリメラーゼアルファサブユニットカルボキシル末端ドメイン (alphaCTD) と相互作用して転写を活性化する方法を示しています. この構造的な洞察は,遺伝子の活性化のための単純な徴募メカニズムをサポートしています.

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