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Updated: Jul 8, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
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15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale

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ヘテロ核のスピンロック緩和率を正確に測定するためのNMR実験

Dmitry M Korzhnev1, Nikolai R Skrynnikov, Oscar Millet

  • 1Protein Engineering Network Centers of Excellence and Departments of Medical Genetics, Biochemistry and Chemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Journal of the American Chemical Society
|September 5, 2002
PubMed
まとめ

研究者らは,一般的な核磁気共鳴 (NMR) 技術は,タンパク質ダイナミクス測定を過大評価することができると発見しました. 特定の (1) H解離法により,異核回転枠のリラクゼーション速度 (R(1) ((rho)) の測定に誤差が生じる.

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