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Updated: Jul 10, 2026

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions
10:52

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions

Published on: September 28, 2017

U1 snRNPタンパク質U1Cは,ベースペアリングがない場合でも,5' スプライスサイトを認識します

Hansen Du1, Michael Rosbash

  • 1Howard Hughes Medical Institute, Department of Biology, MS008, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, USA.

Nature
|September 6, 2002
PubMed
まとめ

複雑な機械であるスプライソームは,初期の相互作用を通じてRNAのスプライシングを開始します. 研究者らは,U1 snRNAではなく,U1Cのタンパク質成分が,特定の5'スペライスサイトを最初に認識する可能性があることを発見しました.

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