関連する実験動画

Updated: May 5, 2026

Visualization of UV-induced Replication Intermediates in E. coli using Two-dimensional Agarose-gel Analysis
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Visualization of UV-induced Replication Intermediates in E. coli using Two-dimensional Agarose-gel Analysis

Published on: December 22, 2010

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AlkB媒介による酸化去甲基化は,Escherichia coliにおけるDNA損傷を逆転させます

Pål Ø Falnes1, Rune F Johansen, Erling Seeberg

  • 1Centre for Molecular Biology and Neuroscience, and Institute of Medical Microbiology, University of Oslo, National Hospital, 0027 Oslo, Norway. pal.falnes@labmed.uio.no

Nature
|September 13, 2002
PubMed
まとめ

バクテリアのAlkBタンパク質は,1-メチラデニンからメチル群を取り除き,DNAの損傷を修復する. この酸化脱メチル化メカニズムは,新しいDNA修復経路を表し,アルキル化ダメージからの細胞回復を支援します.

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