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関連する概念動画

Fundamental Attribution Error01:14

Fundamental Attribution Error

According to some social psychologists, people tend to overemphasize internal factors as explanations—or attributions—for the behavior of other people. They tend to assume that the behavior of another person is a trait of that person, and to underestimate the power of the situation on the behavior of others. They tend to fail to recognize when the behavior of another is due to situational variables, and thus to the person’s state. This erroneous assumption is called the fundamental attribution...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Models of Health Promotion and Illness Prevention II01:18

Models of Health Promotion and Illness Prevention II

The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results from...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Zones of Protection01:16

Zones of Protection

In power systems, the entire setup is divided into protective zones to isolate faults and protect the rest of the network. These zones include generators, transformers, buses, transmission lines, distribution lines, and motors. Each zone can be visualized as a separate room in a house, with each room protected by its own circuit breaker.
Protective zones are defined by closed dashed lines, containing one or more components. A key characteristic of these zones is the strategic placement of...
Marcia's Theory of Identity Status01:26

Marcia's Theory of Identity Status

James Marcia's identity status model provides a framework for understanding how adolescents navigate identity formation through varying degrees of exploration and commitment. Marcia's model builds on Erik Erikson's theories of psychosocial development, focusing specifically on how adolescents reconcile individual aspirations with societal expectations. His model describes identity formation as a dynamic process where adolescents move between different states depending on their level of...

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関連する実験動画

Updated: May 7, 2026

The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
09:12

The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress

Published on: July 4, 2013

進歩ゾーンモデルは進歩の犠牲者なのか?

John W Saunders1

  • 1jsaunder@mbl.edu

Cell
|September 17, 2002
PubMed
まとめ

手足の芽細胞の運命がアピカル外皮脊 (AER) の影響における時間に依存することを示唆する進歩ゾーン (PZ) モデルが異議を唱える. 新しい発見は,脊椎動物の四肢の発達に関するこの支配的な見解が間違っているかもしれないことを示しています.

科学分野:

  • 発達生物学 発達生物学とは
  • 脊椎動物の胚学について
  • リムブ開発は,リムブ地方の発展である.

背景:

  • プログレスゾーン (PZ) モデルは,脊椎動物の四肢の芽の発達について,長い間,支配的な理論でした.
  • このモデルは,メゼンキマ細胞が,アピカル外皮脊 (AER) の下にあるPZで増殖すると仮定しています.
  • 細胞の運命は,細胞がPZ内で過ごす時間の長さに基づいて指定されていると考えられています.

研究 の 目的:

  • 脊椎動物の四肢発達における進歩領域 (PZ) モデルの有効性を評価する.
  • 近距離細胞の運命を特定する際の頂上外皮脊 (AER) の役割を調査する.
  • 確立されたPZモデルに異議を唱える新しい発見を提示する.

主な方法:

  • 肢体の発達に関する既存のデータの分析.
  • 新しい実験結果の統合.
  • 細胞増殖と運命の特異性に関する比較研究.

主要な成果:

  • 新しい発見は,以前の研究と並行して,PZモデルを支持しません.
  • 証拠は,近距離細胞の運命の仕様が,PZで過ごした時間だけに依存しないかもしれないことを示唆しています.

さらに関連する動画

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal
06:45

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal

Published on: April 18, 2017

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes
05:03

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

関連する実験動画

Last Updated: May 7, 2026

The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
09:12

The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress

Published on: July 4, 2013

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal
06:45

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal

Published on: April 18, 2017

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes
05:03

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

  • AERがメゼンキマ細胞の増殖に及ぼす影響は,再評価が必要である.
  • 結論:

    • 脊椎動物の四肢発達に関する支配的な進歩領域 (PZ) モデルは,現在の証拠によって支持されていません.
    • 手足の芽の近距離のパターン化のための代替メカニズムを探求する必要があります.
    • 肢体の発達におけるAERとPZの正確な役割を明らかにするために,さらなる研究が必要である.