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Updated: Mar 17, 2026

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フォークヘッド転写因子FOXO3aは,静止中の細胞を酸化ストレスから保護する

Geert J P L Kops1, Tobias B Dansen, Paulien E Polderman

  • 1Department of Physiological Chemistry, University Medical Center Utrecht and Center for Biomedical Genetics, 3584 CG Utrecht, The Netherlands.

Nature
|September 20, 2002
PubMed
まとめ

静止細胞はFOXO3a転写因子を用いて,マンガン超酸化物変異酶 (MnSOD) を増加させ,酸化ストレスから保護する. このメカニズムは,タンパク質キナーゼB (PKB) に独立して,細胞生存を高め,長寿に関連している可能性があります.

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