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Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping
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1987年と1998年の北極におけるアトピー発生頻度
Tyra Krause1, Anders Koch, Jeppe Friborg
1Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark. tgv@ssi.dk
Lancet (London, England)
|September 21, 2002
まとめ
アロピーというアレルギー症状の頻度は,1987年から1998年の間にグリーンランドの住民で倍増した. このアトピーの増加は,幼児期の暴露だけでなく,環境要因が,その発達に寄与することを示唆しています.
科学分野:
- 環境医学 環境医学
- エピデミオロジー エピデミオロジー
- 免疫学 免疫学とは
背景:
- 非工業化地域におけるアトピー流行に関する客観的なデータは限られている.
- アトピーの頻度に関する以前の研究は,主に工業国に焦点を当てていた.
研究 の 目的:
- グリーンランドの人口における11年間のアトピー頻度の変化を測定する.
- グリーンランドのアトピー流行の年齢分布を調査する.
主な方法:
- 1987年と1998年の集団スクリーニングから15~80歳のグリーンランド人859人の血清サンプルを分析した.
- アトピーは,8つの一般的な吸入アレルゲンに対する特定の免疫グロブリンE (IgE) レベルによって定義されました.
- 統計分析には,リスク比率と信頼区間の計算が含まれていました.
主要な成果:
- アトピーの罹患率は,1987年の10%から1998年の19% (リスク比1.88) に大幅に増加した.
- このアトピー頻度の倍増は,高齢者を含む様々な年齢層で観察されました.
- この増加は,15歳から19歳の年齢層で最も顕著でした.
結論:
- アトピーの罹患率は,グリーンランドの人口の中で10年以上にわたって顕著に増加しています.
- 発見は,アトピーのリスク要因が,幼児期の被曝を超えて広がる可能性があることを示唆しています.
- 多様な集団におけるアトピー発達の環境影響に関するさらなる研究が必要である.
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