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Updated: Jun 19, 2026

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
08:47

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation

Published on: March 5, 2018

カスパース-8変異によって引き起こされるリンパ球活性化におけるプレオトロプ的欠陥は,ヒトの免疫不全を引き起こす

Hyung J Chun1, Lixin Zheng, Manzoor Ahmad

  • 1Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|September 28, 2002
PubMed
まとめ

人体における遺伝的なカスパース-8欠乏症は,ALPSとは異なり,免疫障害を引き起こし,ナイブリンパ球を活性化させ,免疫ホメオスタシスを維持する上で,出生後の重要な役割を明らかにします.

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