慢性的に機能不全した心筋膜における輸血と収縮準備:手術による再血管化後の機能的結果との関係
Jeroen J Bax1, Don Poldermans, Arend F L Schinkel
1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. jbax@knoware.nl
Circulation
|October 2, 2002
まとめ
発血性心筋症では,心筋筋活性を評価することが非常に重要です. 収縮予備の整体 perfusion は,再血管化後の機能的回復を予測しますが,予備のない整体 perfusion は中間的潜在能力を提供します.
科学分野:
- 心臓病学 心臓病学
- 核心臓病の心臓病学について
- エコーカルディオグラフィー エコーカルディオグラフィー
背景:
- 慢性的に機能不全した心筋膜は,収縮準備や perfusion を保持することがあります.
- 缺血性心筋症の患者は,しばしば完ぺきな輸血を示しますが,機能不全のセグメントでは収縮準備が欠けています.
- 再血管化後のこれらのセグメントの機能的結果は不明である.
研究 の 目的:
- 缺血性心筋不全の患者の収縮準備と輸血を評価するために.
- これらの発見と再血管化後の機能的回復を相関させる.
主な方法:
- 発血性心筋症の患者114人が,低用量ドブタミンエコーカルディオグラフィーによる休息 (99m) Tcテトロフォスミンと収縮性予備を用いた輸血の評価を受けた.
- 収縮機能は,外科的再血管化を施す前と9〜12ヶ月後に二次元エコーカルディオグラフィによって評価されました.
主要な成果:
- 1,336の機能不全のセグメントのうち,51%が perfusion を保持し,31%が収縮の準備をしていました.
- perfusion を用いたセグメントの47%には,収縮準備が欠けていました.
- リヴァスキュラライゼーション後の機能的回復を図ったセグメントは,主に不変の perfusion と収縮の準備 (66%) を有していた.
- 機能的回復のないセグメントでは,大部分は, perfusion と contractile reserve (58%) の両方が欠けていました.
- 収縮予備のない整った輸液は,機能回復したセグメントの22%,収縮予備のないセグメントの25%で観察されました.
結論:
- 完ぺきなパルフュージョンと収縮準備の両方のセグメントは,再血管化後の機能回復の高い確率を示しています.
- perfusion と contractile reserve の両方を欠いているセグメントは回復の可能性が低い.
- 完ぺきな perfusion がありますが,収縮準備がないセグメントは,機能的回復の中間的可能性を示しています.
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