53BP1,DNA

Bin Wang1, Shuhei Matsuoka, Phillip B Carpenter

  • 1Verna and Mars McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

Science (New York, N.Y.)
|October 5, 2002
PubMed
まとめ

53BP1タンパク質は,DNA損傷反応と細胞サイクル停止に不可欠です. その枯渇は,重要なチェックポイントを損なっており,放射線治療後のゲノム安定性の維持におけるその役割を強調しています.

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