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Updated: May 5, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
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Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

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ERAAPは,エンドプラズマ網膜内のMHCクラスI分子のためのペプチドをカスタマイズします

Thomas Serwold1, Federico Gonzalez, Jennifer Kim

  • 1Division of Immunology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3200, USA.

Nature
|October 9, 2002
PubMed
まとめ

研究者らは,ペプチドのトリミングに不可欠なエンドプラズマ網膜アミノペプチダゼであるERAAPを特定しました. このプロセスは,MHCクラスI分子を介して抗原を提示するために不可欠であり,腫瘍と病原体のキラーT細胞検出を可能にします.

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