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Updated: Jul 10, 2026

Rare Event Detection Using Error-corrected DNA and RNA Sequencing
10:36

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

ピレン置換DNAのシミュレーションで観察された適合的異質性

Guanglei Cui1, Carlos Simmerling

  • 1Department of Chemistry and Center for Structural Biology, Stony Brook University, Stony Brook, New York 11794-3400, USA.

Journal of the American Chemical Society
|October 10, 2002
PubMed
まとめ

DNAにおけるピレンの置換はアデニンの柔軟性を高め,反/シン塩基対の構成変化を可能にします. 分子ダイナミクスシミュレーションにより,実験データを裏付けるDNA内部の構成変化の経路が明らかになりました.

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