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Updated: Jul 6, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

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ラジカルデカルボキシル化とキノン添加反応によるキノンセスキーターペンの統合合成

Taotao Ling1, Erwan Poupon, Erik J Rueden

  • 1Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0358, USA.

Journal of the American Chemical Society
|October 10, 2002
PubMed
まとめ

新しい急性添加反応により,複合キノンセスキーターペネの合成が可能になる. この方法では,バイサイクルコアをキノンに効率的に結合させ,高酸素の天然製品が得られます.

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