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Updated: May 5, 2026

Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist
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Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist

Published on: April 25, 2018

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クラスIVセマフォリンSema4AはT細胞の活性化を高め,Tim-2と相互作用する

Atsushi Kumanogoh1, Satoko Marukawa, Kazuhiro Suzuki

  • 1Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

Nature
|October 11, 2002
PubMed
まとめ

デンドリット細胞とB細胞に含まれるセマフォリンSema4Aタンパク質は,T細胞の活性化と分化を促進します. ネズミのセマ4Aをブロックすると,実験的な自己免疫性脳髄炎を予防し,免疫反応におけるその役割を明らかにします.

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