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Updated: Jul 6, 2026

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)

Published on: August 21, 2016

ハプロタイプ構造からヒトゲノムにおける最近の陽性選択を検出する

Pardis C Sabeti1, David E Reich, John M Higgins

  • 1Whitehead Institute/MIT Center for Genome Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|October 25, 2002
PubMed
まとめ

科学者たちは,拡張ハプロタイプホモジゴシティ (EHH) を分析することによって,ヒトDNAの最近の自然選択を検出する新しい方法を開発しました. この枠組みは,マラリア耐性遺伝子の選択の遺伝的サインを特定し,人間の進化と医学への洞察を提供しました.

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