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Updated: May 5, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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CNF1は,バクテリアの宿主細胞の侵入のためにRho GTPaseの活性化を制限するために,ユビキチン-プロテアソーム機構を利用します

Anne Doye1, Amel Mettouchi, Guillaume Bossis

  • 1INSERM U452, IFR 50, Faculté de Médecine, 28 avenue de Valombrose, 06107, Nice, France.

Cell
|November 20, 2002
PubMed
まとめ

E. coliからのCNF1毒素は,膀細胞内のRho GTPasesを一時的に活性化させます. この活性化は,Racの分解につながり,細菌の侵入と宿主細胞の運動を可能にします.

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