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Updated: Jun 11, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
11:37

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

Published on: November 29, 2013

モデルアルファヘリコペプチドにおけるD/Hアミド同位体効果

Zhengshuang Shi1, C Anders Olson, Neville R Kallenbach

  • 1Department of Chemistry, New York University, 100 Washington Place, New York, NY 10003, USA.

Journal of the American Chemical Society
|November 21, 2002
PubMed
まとめ

D/Hアミド同位体効果を測定するCm実験では,デナチュラント濃度がタンパク質の安定性測定に与える影響を明らかにしています. グアニジニウム塩化物 (GdmHCl) 濃度の調整は,タンパク質の安定性と水素結合の貢献を正確に比較するために重要である.

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