大動脈吐症の患者における左心房機能の評価は,アフターロードストレスを用いて行う
Circulation
|January 1, 1976
まとめ
重度の大動脈吐 (吐分数>0.50) の患者は,正常な静止射出分数であっても,ストレス下では左心房機能が低下している可能性があります. このストレスに起因する機能障害は,明らかに心不全に先行する可能性があります.
科学分野:
- 心臓病学 心臓病学
- 心血管生理学 心血管の生理学
背景:
- 慢性的な大動脈吐は,左心室機能不全につながる可能性があります.
- ストレスに対する心室の反応を評価することは,疾患の進行を理解するために極めて重要です.
研究 の 目的:
- 負荷の上昇後の慢性的な大動脈吐を有する患者の左心房機能を評価するために.
- この集団におけるストレス誘発性心室機能不全の予測要因を特定する.
主な方法:
- 慢性的な大動脈吐症の14人の患者で左心室機能を評価した.
- アフターロードの上昇を誘発するためにアニオテンシンを使用し,エジェクション分数と脳卒中作業指数を測定しました.
- 患者をアニオテンシンに対するエジェクション分数の反応に基づいてグループに分類した.
主要な成果:
- 7人の患者はエジェクション分数 (A群) を維持し,7人は減少を示した (B群).
- グループBの患者は,異常な脳卒中作業指数を示し,発現した吐 (>0.50) と大きな終末透析体積を示した.
- ストレスによる機能障害は,冠動脈疾患のない患者でも観察されました.
結論:
- 発現した大動脈吐 (吐分数>0.50) と左心室末ダイアストリック容量の増加は,ストレス下における心室機能障害と関連しています.
- ストレス誘発性機能障害は,心不全を前にする左心室機能障害の初期段階を表す可能性があります.
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