水を飲むことは,健康な被験者の ортоスタティック耐性を急激に改善します
Christoph Schroeder1, Victoria E Bush, Lucy J Norcliffe
1Franz-Volhard Clinical Research Center, Medical Faculty of the Charité, Humboldt-University, Berlin, Germany.
Circulation
|November 27, 2002
まとめ
500mLの水を飲むことは,ヘモダイナミック反応と脳血流の調節を強化することによって,健康な個体における正静性耐性を大幅に改善します. この簡単な介入は,立ちあがった時にめまいがと昏睡のような症状を予防するのに役立ちます.
科学分野:
- 生理学 生理学とは
- 心血管科学 心血管科学
- 自律神経系の機能 自律神経系の機能
背景:
- 矯正症状と昏睡が一般的であり,健康な個人と自律機能障害のある人の両方に影響を及ぼします.
- 水の摂取は,重度の自律機能不全の患者において,プレッサー反応を誘発し,正静性低血圧を緩和することが知られている.
研究 の 目的:
- 健康な被験者の ортоスタティック耐性に対する飲料水の影響を調査する.
- 急性水分摂取が,体の血圧を維持する能力を改善し,立っているときに昏睡を防ぐことができるかどうかを判断する.
主な方法:
- 13人の健康な被験者を対象としたランダム化,制御,クロスオーバー研究.
- 被験者は,頭を上向きに傾け,下部に負の圧力をかけられる前に,500mLまたは50mLのミネラルウォーターを摂取した.
- 測定には,指と腕の血圧,心拍数,胸の阻害,脳の血流速度が含まれていました.
主要な成果:
- 500mLの水を摂取すると, ортоスタティック耐性が平均5分 (P<0.001) 大きく増加しました.
- この量の水分摂取は,外周抵抗性の上昇により,仰向け状態の血圧がわずかに上昇した.
- 水の消費は,静止性ストレス中に心拍数増加と脳卒中の体積減少を鈍化し,脳の血流調節を改善しました.
結論:
- 水を飲むことは,すぐに血液動力学的反応を誘発し,健康な個体では脳血管の調節を変化させます.
- これらの生理学的変化は,直立した姿勢を許容する能力の実質的な改善と直接関連しています.
キーワード:
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