関連する実験動画

Updated: Aug 6, 2026

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening
08:34

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening

Published on: October 16, 2015

フェニララニンアナログのフェニララニル-tRNA合成酵素への結合のための仮想スクリーニング

Pin Wang1, Nagarajan Vaidehi, David A Tirrell

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

Journal of the American Chemical Society
|November 28, 2002
PubMed
まとめ

この研究は,フェニララニル-tRNA合成酵素 (PheRS) にフェニララニルアナログがどの程度結合するかを予測する計算方法であるHierDockを導入しています. このツールは,アミノ酸アナログを仮想的にスクリーニングし,タンパク質工学研究における時間と資源を節約するのに役立ちます.

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