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関連する概念動画

Protein Folding01:22

Protein Folding

Overview
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Protein Folding01:25

Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...

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関連する実験動画

Updated: Jul 19, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
12:33

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

解剖:環境が変化したときに自主的に構造を再構成する自己組み立ての集積物.

Chengde Mao1, Venkat R Thalladi, Daniel B Wolfe

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

Journal of the American Chemical Society
|December 6, 2002
PubMed
まとめ

研究者は,再構成可能なメソスケールセルフアセンブリを使用して,適応構造を開発しました. ミリメートルスケールの物体は,水相密度に基づいて2つの異なる構造に自己組み立てます.

さらに関連する動画

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

関連する実験動画

Last Updated: Jul 19, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
12:33

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

科学分野:

  • マテリアルサイエンス 材料科学
  • 超分子化学 超分子化学
  • ソフトマター物理学 ソフトマター物理学

背景:

  • 適応性のある構造は,ダイナミックな機能性を提供します.
  • 再構成可能な自己組み立ては,複雑な材料を作成するための重要な戦略です.
  • メソスケールシステムは,分子スケールとマクロスケールとの間のギャップを埋めます.

研究 の 目的:

  • 適応性構造の設計のための新しい戦略を提示する.
  • ミリメートルスケールのオブジェクトの再構成可能な自己組み立てを実証するために.
  • 環境刺激に基づく集積物の形成を制御するために.

主な方法:

  • ミリメートルスケールのブロックの設計.
  • 水分とフルオロデカリン相の間のインターフェースを利用する.
  • 水相密度を調節して直接自己組み立て.

主要な成果:

  • 2つの異なる正規の集積物に自己組み立てに成功しました.
  • 刺激反応再構成の実証.
  • 溶液密度の変化によって達成される集合体形態の制御.

結論:

  • 提案された戦略は,適応性のある材料の作成を可能にします.
  • メソスケールセルフアセンブリは,応答性の高い構造のための汎用性のあるプラットフォームを提供します.
  • 密度依存自己組み立ては,構造制御のための調整可能なメカニズムを提供します.