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Updated: Aug 17, 2026

Assaying Protein Kinase Activity with Radiolabeled ATP
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ミトゲン活性化タンパク質キナーゼ経路は,ERK,JNK,p38タンパク質キナーゼによって媒介されます

Gary L Johnson1, Razvan Lapadat

  • 1Department of Pharmacology, University of Colorado Health Sciences Center, Denver, CO 80262, USA. gary.johnson@uchsc.edu

Science (New York, N.Y.)
|December 10, 2002
PubMed
まとめ

ミトゲン活性化タンパク質キナーゼ (MAPK) は,多細胞生物における重要なシグナル伝達酵素である. 特定のMAPK経路を標的にする阻害剤は,がん,関節リウマチ,喘息,自己免疫疾患の治療に潜在力を示しています.

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