関連する実験動画

Updated: Jun 10, 2026

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

不平等なクロスオーバーによって繰り返されたDNA配列の進化.

G P Smith

    Science (New York, N.Y.)
    |February 13, 1976
    PubMed
    まとめ

    特殊なメカニズムから生じると考えられている高度に繰り返されるDNA配列は,ランダムな変異と不平等な交差を通して自然に形成されることがあります. これは,タンデム・リピートが,強い選択的圧力を受けていないDNAの一般的な状態であることを示唆しています.

    さらに関連する動画

    Following the Dynamics of Structural Variants in Experimentally Evolved Populations04:52

    Following the Dynamics of Structural Variants in Experimentally Evolved Populations

    Published on: February 3, 2023

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR06:18

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

    Published on: July 11, 2025

    関連する概念動画

    Gene Evolution - Fast or Slow?02:05

    Gene Evolution - Fast or Slow?

    The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
    In contrast, regions which code...
    Gene Conversion02:08

    Gene Conversion

    Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
    Evolutionary Relationships through Genome Comparisons02:54

    Evolutionary Relationships through Genome Comparisons

    Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
    Gene Duplication and Divergence02:37

    Gene Duplication and Divergence

    The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
    The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
    Gene Evolution - Fast or Slow?02:05

    Gene Evolution - Fast or Slow?

    The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
    In contrast, regions which code...
    Gene Conversion02:08

    Gene Conversion

    Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...