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モエシンは,Rho経路に敵対して機能し,上皮質の完全性を維持します

Olga Speck1, Sarah C Hughes, Nicole K Noren

  • 1DCMB Group, Department of Biology, Duke University, Box 91000, Durham, North Carolina 27708, USA.

Nature
|January 4, 2003
PubMed
まとめ

この研究では,上皮細胞のタンパク質であるモエシンが,アクチンアセンブリを調節し,Rho GTPase活性に対抗することによって,細胞構造と極性を維持することを明らかにした. モエシンが失われると,細胞は上皮の特性を失い,移動するようになります.

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