ナルキソンによる刺激による鎮痛の対抗性,ナルコティック対抗剤であるナルキソンによる刺激による鎮痛の対抗性

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Updated: Aug 12, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
07:23

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

H Akil, D J Mayer, J C Liebeskind

    Science (New York, N.Y.)
    |March 5, 1976
    PubMed
    まとめ

    脳の刺激による鎮痛は,ナルキソンによって部分的に逆転します. より高いナロキソン用量は逆転を増加させず,痛み緩和に内生性オピオイドの関与を示唆しました.

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