磁気共鳴画像ガイドによるトランスキャセターの閉塞は,心房隔膜の欠陥の閉塞です
Carsten Rickers1, Michael Jerosch-Herold, Xudong Hu
1University of Minnesota, Department of Radiology, Minneapolis, Minn, USA.
Circulation
|January 8, 2003
まとめ
この研究は,磁気共鳴画像 (MRI) が,心房隔膜欠陥 (ASD) のトランスカテーター閉塞を導くことができることを示しています. リアルタイムMRIは,ASDのサイズと心臓の変化を正確に測定し,デバイスの成功展開を可能にします.
科学分野:
- 心血管画像検査についてです.
- 介入性心臓病学 介入性心臓病学
- 医療機器技術 医療機器技術について
背景:
- 心臓MRI技術の進歩は,新しい診断および介入用途を可能にします.
- 心房隔膜欠陥 (ASD) は,介入を必要とする一般的な先天性心疾患です.
研究 の 目的:
- セクチューム型ASDのトランスキャセター閉塞に対するMRIの能力を評価する.
- 同じMRI検査でASDのサイズと右心室の体積の変化を評価する.
主な方法:
- 豚のモデルにおけるASDの皮膚経由的な形成.
- 高解像度MRIでASDの画像とサイズを測定し,死後の検査と相関しています.
- トランスキャセター装置の展開のための新しいMRガイドワイヤーのリアルタイムMR光学.
- シネ・MRIで,介入前と後の右心房と心室の体積を計算する.
主要な成果:
- MRIはASDの直径を正確に決定し,死後の発見と良好に相関しています (r=0.97).
- リアルタイムのMRIガイドの下でアンプラッツァ・セプトル・オクラダの追跡と展開が成功しました.
- ASD閉塞後の右心房と心室の体積の有意な減少 (P<0.005).
結論:
- 血管内アンテナガイドワイヤを使用したトランスキャテーターASD閉塞には,リアルタイムMRI誘導が可能である.
- 高解像度のMRIは,ASDの正確なサイズ測定と,心臓の体積に対する治療効果の即時評価を可能にします.
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