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Updated: Jul 10, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
09:18

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

死を制御する経路におけるPHAPタンパク質とプロチモシンアルファの特徴的な役割

Xuejun Jiang1, Hyun-Eui Kim, Hongjun Shu

  • 1Howard Hughes Medical Institute, Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|January 11, 2003
PubMed
まとめ

新しい小分子であるPETCMは,PHAP/ProT経路を調節することによって,がん細胞におけるカスパース-3を活性化します. この経路はアポトーシスを調節し,ProTは抑制し,PHAPはカスパースの活性化を促進する.

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Phosphorylation01:02

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