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Updated: Jul 6, 2026

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
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アルファ L I ドメインの構造とICAM-1との複合体は,インテグリン調節のための形状変化経路を示しています

Motomu Shimaoka1, Tsan Xiao1, Jin-Huan Liu2

  • 1The Center for Blood Research, Department of Pathology, Department of Anesthesia, Department of Pediatrics, Boston, Massachusetts 02115.

Cell
|January 16, 2003
PubMed
まとめ

ICAM-1に結合したインテグリンアルファLベータ2Iドメイン構造は,そのオープンコンフォームを明らかにします. アロステリック信号とリガンド結合は構造変化を誘導し,インテグリン親和性を変化させます.

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