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Updated: May 3, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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ヒトヒストンメチルトランスフェラーゼSET7/9の構造と触媒機構

Bing Xiao1, Chun Jing, Jonathan R Wilson

  • 1Structural Biology Group, National Institute for Medical Research, Mill Hill, London NW7 1AA, UK.

Nature
|January 24, 2003
PubMed
まとめ

人間のSET7/9は,他のSETタンパク質とは異なり,ユニークなモノメチラーゼです. その結晶構造は,ヒストンの標的とコファクターが結合する方法を明らかにし,メチル化特異性と反応機構を説明します.

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