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Updated: Aug 1, 2026

Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum
09:40

Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum

Published on: September 20, 2011

異なる受容体は,ATPとGTPの診断パターンを生み出します

Shawn C McCleskey1, Michael J Griffin, Stephen E Schneider

  • 1University of Texas at Austin, Department of Chemistry and Biochemistry, Austin, Texas 78712, USA.

Journal of the American Chemical Society
|January 30, 2003
PubMed
まとめ

この研究は,核酸塩酸塩を検出するための新しいセンサー配列を導入し,各分析物に対してユニークな指紋応答を提供します. この進歩により,アデノシン三リン酸および関連する化合物が含まれる溶液の選択的かつほぼリアルタイムなデジタル分析が可能になります.

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G-protein Coupled Receptors01:21

G-protein Coupled Receptors

G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
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GTPases and their Regulation

Guanine nucleotide-binding proteins (G-proteins), also known as GTPases, are a superfamily of proteins that regulate many cellular processes, such as cell signaling, vesicular transport, and the regulation of cell shape and motility. Mutation or dysfunction of these proteins can lead to disease. There are around 40,000 known G-proteins that can broadly be classified into two groups ‒  small G-proteins consisting of a single domain and large multi-domain G-proteins.
Large G-proteins, also known...
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ATP Driven Pumps I: An Overview

ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
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ATP Driven Pumps II: P-type Pumps

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Activation and Inactivation of G Proteins

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