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Updated: Jan 5, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
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肝臓腫瘍の発達. c-Junは,p53のプロアポプトシス作用を阻害する

Robert Eferl1, Romeo Ricci, Lukas Kenner

  • 1Research Institute of Molecular Pathology (IMP), Dr. Bohrgasse 7, A-1030, Vienna, Austria.

Cell
|January 30, 2003
PubMed
まとめ

転写因子c-Junは,アポトーシスを抑制することによって,早期の肝がん発症に不可欠です. マウスにおけるc-Junの無活性化により,p53活性とアポトーシスの増加により,腫瘍の成長が減少した.

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