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B-アルキルスズキマクロサイクライゼーションを用いた (+) -フォマクチンaの総合成

Peter J Mohr1, Randall L Halcomb

  • 1Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215, USA.

Journal of the American Chemical Society
|February 13, 2003
PubMed
まとめ

研究者は,複雑な分子である (+) -フォマクチンAの全合成を達成しました. 重要なステップは,スズキのマクロサイクライゼーションで,トリスブスティチュートされたオレフィンを成功裏に組み込み,敏感なフラン環を保存しました.

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