甲状腺がん (甲状腺がん) は,甲状腺がんの
1Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Texas, Houston 77030, USA. sisherma@mdanderson.org
Lancet (London, England)
|February 14, 2003
まとめ
甲状腺がんの治療には手術と放射性ヨウ素が含まれ,甲状腺ホルモンの抑制が再発防止に役立ちます. 進行した甲状腺がんには新しい治療法が必要であり,遺伝検査は遺伝性症候群の治療に役立ちます.
科学分野:
- 腫瘍学 腫瘍学
- エンドクリノロジー エンドクリノロジー
背景:
- 甲状腺がんは希少で,軟弱なパピラリから致死的なアナプラスティックタイプまで様々です.
- 診断と初期管理のための確立されたガイドラインが存在し,しばしばマルチモダリティの治療を推奨します.
- 多様性アプローチを支持する見通し試験からの証拠は限られている.
研究 の 目的:
- 甲状腺がんの現在の理解と管理を要約するために.
- 先進的および高リスクの甲状腺がんに対する改善された治療法の必要性を強調する.
- 遺伝性甲状腺癌症候群における遺伝子検査の役割を強調する.
主な方法:
- 甲状腺がんの現在の治療戦略のレビュー.
- 外科的切除,放射性ヨウ素療法,甲状腺ホルモン抑制についての議論.
- 遺伝性甲状腺がん症候群の遺伝子検査を検討する.
主要な成果:
- 外科的切除は,局所的な制御のための主要な治療法です.
- 補助的な放射性ヨウ素療法は,パピラおよび卵泡型に共通しています.
- 甲状腺ホルモンの抑制は,特定の甲状腺がんのタイプの再発を予防することができます.
- 進行性の転移性疾患には限られた利点があり,新しい治療戦略が必要になります.
結論:
- 多学科ケアと患者教育は,情報に基づいた意思決定に不可欠です.
- 早期の診断と介入,特に遺伝性症候群では,治療結果を改善することができます.
- 侵襲的および転移性甲状腺がんの治療方法の新規化が著しく必要とされています.
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