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Updated: Jul 15, 2026

Sampling Human Indigenous Saliva Peptidome Using a Lollipop-Like Ultrafiltration Probe: Simplify and Enhance Peptide Detection for Clinical Mass Spectrometry
08:37

Sampling Human Indigenous Saliva Peptidome Using a Lollipop-Like Ultrafiltration Probe: Simplify and Enhance Peptide Detection for Clinical Mass Spectrometry

Published on: August 7, 2012

ヒト中性粒子のアルファ-デフェンシンをプロペプチドなしでインビトロで生産的に折りたたむ

Zhibin Wu1, Robert Powell, Wuyuan Lu

  • 1Institute of Human Virology, University of Maryland Biotechnology Institute, 725 West Lombard Street, Baltimore, MD 21201, USA.

Journal of the American Chemical Society
|February 27, 2003
PubMed
まとめ

人間の中性粒子のアルファ-デフェンシン (HNP) は,その抑制性プロペプチドなしで効率的に生成することができます. このブレークスルーは,純粋なHNPを生成するためのスケーラブルな方法を提供し,抗菌薬の研究と潜在的なHIV-1治療に価値があります.

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Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group07:49

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関連する概念動画

Protein Folding01:22

Protein Folding

Overview
Protein Folding01:25

Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

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In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
Fibrous Proteins00:55

Fibrous Proteins

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Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Peptidoglycan Synthesis01:28

Peptidoglycan Synthesis

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