Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

320
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
320
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

277
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
277
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

464
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
464
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

262
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
262
Pneumothorax-II01:27

Pneumothorax-II

852
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
852
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

3.1K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
3.1K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Microbe-induced galls and plant defence: metabolite crosstalk in a co-evolutionary battle.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same author

GA20ox1-mediated GA4 production promotes inflorescence stem growth in Arabidopsis via inner-layer cell proliferation.

Plant & cell physiology·2026
Same author

Cytokinin receptor AHK3 influences leaf size by modulating trans-zeatin-type cytokinin levels in xylem.

Plant & cell physiology·2026
Same author

Rice EMF3 Alleles Adjust Flower Opening Time to Enhance the Seed Setting Rate Under High Temperature Stress.

Plant biotechnology journal·2026
Same author

<i>N</i>-glucosylation of indole-3-acetyl amino acids modulates auxin metabolism and growth traits in <i>Oryza sativa</i>.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Immune activation suppresses reproductive growth in Arabidopsis through cytokinin signaling.

Current biology : CB·2026

関連する実験動画

Updated: Jan 9, 2026

Pulmonary Embolism III: Nursing Management
01:27

Pulmonary Embolism III: Nursing Management

Published on: June 19, 2025

320

ダイネインの構造とパワーストローク

Stan A Burgess1, Matt L Walker, Hitoshi Sakakibara

  • 1Astbury Centre for Structural Molecular Biology & School of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, UK. s.a.burgess@leeds.ac.uk

Nature
|March 1, 2003
PubMed
まとめ
この要約は機械生成です。

重要なマイクロチューブルモーターであるダイネインアタパースは,パワーストロークメカニズムを通じて力を発生します. ダイネインcの構造的変化は,リンカーの柔軟性と茎の硬さが分子縮小と移動をどのように誘導するかを明らかにします.

さらに関連する動画

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Published on: June 19, 2025

277
Pulmonary Embolism I: Introduction
01:29

Pulmonary Embolism I: Introduction

Published on: June 19, 2025

464

関連する実験動画

Last Updated: Jan 9, 2026

Pulmonary Embolism III: Nursing Management
01:27

Pulmonary Embolism III: Nursing Management

Published on: June 19, 2025

320
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Published on: June 19, 2025

277
Pulmonary Embolism I: Introduction
01:29

Pulmonary Embolism I: Introduction

Published on: June 19, 2025

464

科学分野:

  • バイオケミストリー バイオケミストリー
  • 分子生物学は分子生物学である.
  • 細胞生物学 細胞生物学

背景:

  • ディネインアタパースは,細胞の輸送と運動に関与する微小管の重要なモーターである.
  • ダイネインが力を生み出す正確なメカニズムは,ほとんど不明のままである.
  • ダイネインの機能を理解することは,様々な生物学的プロセスを理解するために非常に重要です.

研究 の 目的:

  • ダイネインにおける力発生の構造的メカニズムの解明 c.
  • パワーストロックの異なる段階のダイネインcを視覚化します.
  • ダイネイン運動活動の分子基礎についての洞察を提供するため.

主な方法:

  • 電子顕微鏡を用いて,ダイネインの高解像度イメージングを行いました.
  • 構造変化を分析するために,高度な画像処理技術を採用した.
  • 核酸リガンドの存在と欠如におけるダイネイン構造を調べた.

主要な成果:

  • ダイネインの茎と茎の両方の構成要素の柔軟性を特定した.
  • 左側の領域と茎の硬さにおける有意な形状の変化が観察されました.
  • 分子縮小と相関する茎の先端の~15 nmの位移を定量化しました.

結論:

  • この研究は,ダイネインパワーストロックの生成のための新しいメカニズムを明らかにしています.
  • ダイネイン構造の形状の変化は,力生成と直接関連しています.
  • 発見は,ダイネイン媒介の運動性を理解するための構造的基礎を提供します.