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Updated: Jul 11, 2026

Multi-parameter Measurement of the Permeability Transition Pore Opening in Isolated Mouse Heart Mitochondria
13:42

Multi-parameter Measurement of the Permeability Transition Pore Opening in Isolated Mouse Heart Mitochondria

Published on: September 7, 2012

MCC-134は単一の薬剤であるため,表面のATPに敏感なカリウムチャネルを開き,ミトコンドリアのATPに敏感なカリウムチャネルを遮断し,前置条件化を抑制します

Norihito Sasaki1, Mitsushige Murata, Yiru Guo

  • 1Laboratory of the Institute of Molecular Cardiobiology, Johns Hopkins University, Baltimore, MD 21205, USA.

Circulation
|March 5, 2003
PubMed
まとめ

MCC-134は心臓表面のカリウムチャネルを開くが,ミトコンドリアのカリウムチャネルを阻害する. この薬は,前置条件の心臓保護効果を阻害し,心臓の保護におけるミトコンドリアのK ((ATP) チャンネルの役割を強調します.

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