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Updated: Jun 23, 2026

Visualizing Neuroblast Cytokinesis During C. elegans Embryogenesis
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Par複合体は,細胞骨格タンパク質Lglglをリン酸化することによって,非対称な細胞分裂を誘導する

Jörg Betschinger1, Karl Mechtler, Juergen A Knoblich

  • 1Research Institute of Molecular Pathology, Dr Bohr Gasse 7, 1030 Vienna, Austria.

Nature
|March 12, 2003
PubMed
まとめ

Parタンパク質複合体は,Lethal (2) 巨大幼虫 (Lgl) をリン酸化することによって,細胞の運命決定因子の誤局化を防ぐ. このリン酸化はLglの活動を制限し,ドロソフィラのニューロブラストにおける適切な細胞分裂と子細胞運命を決定します.

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