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Updated: May 8, 2026

Detection of Lung Tumor Progression in Mice by Ultrasound Imaging
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エッジホッグ・シグナリングは,呼吸道上皮原体および小細胞肺がんにおけるエッジホッグシグナリングである

D Neil Watkins1, David M Berman, Scott G Burkholder

  • 1Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA. nwatkins@jhmi.edu

Nature
|March 12, 2003
PubMed
まとめ

ソニック・ヘッジホッグ (Shh) 信号を含むヘッジホッグ (Hh) 経路は,呼吸道上皮質の修復と発達に不可欠です. 小細胞肺がん (SCLC) での活性化は,この攻撃的な悪性腫瘍の治療標的を示唆しています.

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