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Updated: Jul 6, 2026

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

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銅 (((I) 触媒化アジドアルキン [3 + 2]サイクロアディションによるバイオ結合

Qian Wang1, Timothy R Chan, Robert Hilgraf

  • 1Departments of Chemistry and Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Journal of the American Chemical Society
|March 13, 2003
PubMed
まとめ

銅で触媒化されたサイクロアディションは,水中のアジドとアルキンを用いてタンパク質を効率的に結合します. 特殊なリガンドは銅を安定させ,タンパク質の損傷を防止し,信頼性の高い生物結合を可能にします.

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