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Updated: Aug 10, 2026

Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators
06:31

Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators

Published on: November 27, 2015

非機能化,アルファエピメリゼーション可能な非血性ケトンとアルデヒドは,イミンの結晶化誘発のダイナミック解像によって得ることができる

Janez Kosmrlj1, Leland O Weigel, David A Evans

  • 1Chemical Process R&D, Lilly Research Laboratories, Indianapolis, IN 46285-4813, USA. janez.kosmrlj@uni-lj.si

Journal of the American Chemical Society
|March 13, 2003
PubMed
まとめ

この研究では,単純な結晶化誘発ダイナミック解像度 (CIDR) 方法を導入し,ラセミアルデヒドとケトンを効率的に単一のエナチオマーに変換します. このプロセスは,高収量とエナティオメール過剰を達成し,キラル化合物の合成のための実用的なアプローチを提供します.

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