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Updated: Jul 18, 2026

Detection of Protein Ubiquitination
09:00

Detection of Protein Ubiquitination

Published on: August 19, 2009

Pirh2は,p53誘発のユビキチン-タンパク質リガゼであり,p53の分解を促進する

Roger P Leng1, Yunping Lin, Weili Ma

  • 1Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9.

Cell
|March 26, 2003
PubMed
まとめ

Pirh2は,新しいE3ユビキチンリガゼで,p53腫瘍抑制剤の分解を促進することによって,p53腫瘍抑制剤を否定的に調節します. この相互作用はフィードバックループを形成し,p53のレベルと機能を制御します.

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Purification of Ubiquitinated p53 Proteins from Mammalian Cells10:55

Purification of Ubiquitinated p53 Proteins from Mammalian Cells

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